Product ID

G418 disulfate salt：C20H40N4O10 ˙2H2SO4    Mr：692.71

Potency  ：> 700mg/mg

Form/Solubility:  powder/water and methanol

 Applications

G418 blocks polypeptid synthesis and inhibit elongation.  It is used as a selective agent for transfected eucaryotic cells, such as mammalian and yeast cells.  Recommended for use in selection application at 100-1000mg/ml.

Background information
?       Cell culture tested: A549, H460, H520, H146, CCM1 and NIH/3T3 (Fig. 1)

  Figure 1: Growth curve of NIH3T3 cells with 10 different G418 concentrations after 5 days (left) and 10 days (right) treatment.